Relationship of coronary calcinosis and local fat deposts in patients with coronary artery disease

Highlights . Taking into account the connection between increase in volume of myocardial adipose tissue and vessels with massive calcification coronary arteries heart disease, morphometry epicardial perivascular during routine tomographic examinations can be considered as a non-invasive technique for determining surrogate marker severe lesion. Aim To evaluate relationship artery (CA) morphometric parameters local fat depots patients disease (CHD). Methods 125 stable aged 59±8.9 years were examined. Visualization depots, abdominal (CC) was performed using multislice computed tomography subsequent post-processing images on Siemens Leonardo workstation (Germany). Non-contrast magnetic resonance imaging used to determine EAT thickness. Results Coronary detected 95.2% examined (n = 119). There higher indices thickness right left ventricles case CC, pericardial at level trunk coronary, anterior descending, circumflex arteries, increased depot comparison who had moderate medium CC. Conclusion An myocardium CAD is associated calcification, which reflected pathogenetic “adipovascular” continuum, characterized by stimulation adipogenesis against background atherocalcinosis arteries. Morphometry studies lesions.